Schizophrenia

Home » Schizophrenia » Risk Factors for Schizophrenia

Risk Factors for Schizophrenia

Risk factors for schizophrenia include the following:

• Genetics
• Abnormalities in brain structure
• Abnormal brain chemistry
• Birth trauma
• Seasonality (exposure to a virus)
• Environmental conditions

Heredity is the most well established schizophrenia risk factor. People who have immediate family members with schizophrenia have a 10% chance of developing the disorder, ten times that of the general population. Other personality disorders, including those with psychotic symptoms, also seem to be more prevalent in families with schizophrenia. Despite the chance for inheritance, the number of children born to parents with schizophrenia doubled in the first 50 years of the 20th century.

A recent study that seems to support a genetic cause of schizophrenia suggests that identical twins stand a 50% to 85% chance of sharing the disease. Furthermore, it shows this to be about three times that for fraternal twins. Still, most studies fail to identify the exact mechanism and location of genetic transmission, though they do identify possible genes and chromosomes.

Because not all identical twins share the disease, and because people without familial history develop it, it is likely that there are other physiological and environmental risk factors involved.

Abnormal brain structure is found consistently in people with schizophrenia. This includes enlarged ventricles and asymmetrical hemispheres. Computerized functional imaging of the brain has found decreased blood flow to the frontal lobes of people with schizophrenia. These types of brain abnormalities forecast certain symptoms, like loss of attention, difficulty with abstract thinking, and the inability to solve problems.

Some evidence suggests that infants who experience birth trauma or complications while in the womb are at greater risk for schizophrenia. Maternal illness may play a part as well. A mother who contracts a virus like the flu, especially during her second trimester, may increase the risk for her child. It is not known, whether the virus itself or the immune response to it increases the risk.

Some studies have shown that winter birth may be assoicated with schizophrenia, especially during immune response and illness. Furthermore, viruses in the womb are more common during the winter months. This has led some researchers to consider intrauterine viral infection during the winter as a risk factor. The same link, however, is found for major mood disorders, like bipolar disorder.

Environmental factors and stress are thought to trigger the onset of schizophrenia. For example, moving, troubled relationships, problems at work, or substance abuse may aggravate the constellation of risk factors and lead to psychosis.

© 1998-2009 Healthcommunities.com, Inc. All Rights Reserved.

Schizophrenia Resources

	Join Our Schizophrenia Forum Do you have a question, want to share medical advice, or just need to discuss your situation with someone else having a similar experience? The healthchannels forum is a resource for everyone to share and discuss their health and medical needs with others.	Advertising Disclaimer
	Living with...Share your story Do you have a personal health story that you would like to share with others? As a source of free patient education, our goal is to provide our users with trustworthy information and support from others. That's why we've started our "Living with..." sections.
	Our "Living With..." support pages are a place to share experiences about living with a certain condition, disease, disorder, or illness and for loved ones of those dealing with health-related issues. Many people, especially when newly diagnosed, find comfort in knowing that others are having a similar experience. Help others by sharing your story. View stories already submitted.
	Stay Updated Sign up for our newsletter and receive important updates on the medical conditions that are most important to you.
To quickly access health information from your website's browser, download Healthcommunities.com's healthchannels toolbar. Advertising Disclaimer